TREAT TB, a multi-year project funded by USAID, seeks to contribute to new knowledge regarding shorter, more tolerable treatment regimens for multi-drug resistant tuberculosis (MDR-TB) through clinical trials of priority research questions, targeted operational research benefitting global, regional, and country TB control efforts, and field evaluations of diagnostic tools.
STREAM Clinical Trial
As part of TREAT TB, the STREAM Clinical Trial is being implemented to evaluate the efficacy and safety of novel treatments for MDR-TB. The trial represents a unique collaboration between USAID, Janssen Pharmaceuticals, The Union and The Union’s affiliate, Vital Strategies. Preliminary results from Stage 1 of the STREAM trial were announced in October 2017. Final results are expected in late 2018.
Trial Overview | Trial Sites | Study Team | Community Engagement
Operational research plays a key role in successful TB control efforts. Since its launch in 2008, TREAT TB has trained public health professionals in high TB burden countries to conduct operational research independently.
Overview | Peru | South Africa | India | Philippines
TREAT TB provides technical assistance to national TB programs to improve TB control. In the Philippines, TREAT TB is providing a comprehensive package of technical assistance to support national scale-up of the standard short treatment regimen for MDR-TB.
TA Overview | Philippines MDR-TB